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Paolo Sportoletti Selected Research

Nuclear Export Signals (Nuclear Export Signal)

12/2021Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML.
1/2021A Curious Novel Combination of Nucleophosmin (NPM1) Gene Mutations Leading to Aberrant Cytoplasmic Dislocation of NPM1 in Acute Myeloid Leukemia (AML).

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Paolo Sportoletti Research Topics

Disease

19B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
12/2022 - 08/2013
9Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
12/2021 - 11/2009
5Neoplasms (Cancer)
12/2021 - 04/2008
5Leukemia
06/2021 - 05/2015
4COVID-19
01/2022 - 01/2020
3Infections
01/2022 - 09/2011
3Lymphoma (Lymphomas)
01/2020 - 10/2015
2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL)
06/2022 - 01/2020
2Hematologic Neoplasms (Hematological Malignancy)
12/2021 - 01/2018
2Graft vs Host Disease (Graft-Versus-Host Disease)
12/2020 - 01/2018
2Inflammation (Inflammations)
11/2017 - 01/2017
2Carcinogenesis
04/2010 - 04/2008
1Mantle-Cell Lymphoma (Lymphoma, Mantle Cell)
10/2022
1Waldenstrom Macroglobulinemia (Macroglobulinemia)
08/2022
1Disease Progression
12/2021
1Neutropenia
12/2021
1Chronic Obstructive Pulmonary Disease (COPD)
06/2021
1Philadelphia Chromosome
01/2021
1Exanthema (Rash)
01/2021
1Lymphomatoid Papulosis
01/2021
1Pruritus (Itching)
01/2021
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
01/2021
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
01/2021
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
01/2020
1Bone Marrow Failure Disorders
10/2019
1Dyskeratosis Congenita (X-Linked Dyskeratosis Congenita)
10/2019
1Paraproteinemias (Monoclonal Gammopathy)
06/2019
1Lymphadenopathy
11/2017
1Neuroinflammatory Diseases
11/2017
1Melanoma (Melanoma, Malignant)
01/2017
1Pneumonia (Pneumonitis)
01/2017
1Hypersensitivity (Allergy)
01/2017
1Cystic Fibrosis (Mucoviscidosis)
01/2017
1Lymphocytosis
10/2015
1Acute Promyelocytic Leukemia
05/2015
1Sarcoma (Soft Tissue Sarcoma)
04/2015
1Hairy Cell Leukemia
02/2015
1Myelodysplastic Syndromes (Myelodysplastic Syndrome)
09/2012
1Chromosome Aberrations (Chromosome Abnormalities)
01/2011
1Prostatic Intraepithelial Neoplasia
04/2010
1Prostatic Neoplasms (Prostate Cancer)
04/2010

Drug/Important Bio-Agent (IBA)

13ibrutinibIBA
10/2022 - 11/2017
8NucleophosminIBA
12/2021 - 04/2008
5Rituximab (Mabthera)FDA Link
12/2021 - 01/2021
5Proteins (Proteins, Gene)FDA Link
12/2021 - 04/2008
3venetoclaxIBA
01/2022 - 01/2021
2Chlorambucil (Leukeran)FDA Link
12/2022 - 01/2020
2obinutuzumabIBA
12/2022 - 01/2020
2Agammaglobulinaemia Tyrosine KinaseIBA
10/2022 - 12/2019
2Tyrosine Kinase InhibitorsIBA
01/2022 - 01/2021
2Nuclear Export Signals (Nuclear Export Signal)IBA
12/2021 - 01/2021
2Oxygen (Dioxygen)IBA
12/2021 - 01/2020
2idelalisibIBA
08/2021 - 04/2021
2Biological ProductsIBA
02/2015 - 01/2011
1Small Interfering RNA (siRNA)IBA
06/2022
1Glycogen Synthase (Synthase I)IBA
06/2022
1Protein CIBA
12/2021
1Tryptophan (L-Tryptophan)FDA Link
12/2021
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
03/2021
1Bendamustine HydrochlorideFDA Link
01/2021
1Imatinib Mesylate (Gleevec)FDA Link
01/2021
1Calcium-Transporting ATPases (Ca2+ ATPase)IBA
01/2020
1Ribosomal RNAIBA
10/2019
1Small Nucleolar RNA (snoRNA)IBA
10/2019
1Immunoglobulin A (IgA)IBA
06/2019
1Bepridil (Vascor)FDA Link
01/2018
1Biomarkers (Surrogate Marker)IBA
01/2018
1Biological FactorsIBA
11/2017
1Hemoglobins (Hemoglobin)IBA
11/2017
1CateninsIBA
11/2017
1IntegrinsIBA
11/2017
1Interleukin-9 (Interleukin 9)IBA
01/2017
1Protein Isoforms (Isoforms)IBA
01/2017
1Protein Kinases (Protein Kinase)IBA
01/2017
1RNA (Ribonucleic Acid)IBA
01/2017
1Messenger RNA (mRNA)IBA
01/2017
1VemurafenibIBA
01/2017
13' Untranslated Regions (3' UTR)IBA
01/2017
1GlucocorticoidsIBA
10/2015
1Antineoplastic Agents (Antineoplastics)IBA
10/2015
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
05/2015
1Tretinoin (Retinoic Acid)FDA LinkGeneric
05/2015
1Oncogene Proteins (Oncogene Protein)IBA
05/2015
1Arsenic Trioxide (Trisenox)FDA Link
05/2015
1NF-kappa B (NF-kB)IBA
08/2013
1CCAAT-Enhancer-Binding ProteinsIBA
09/2012
1PhosphoproteinsIBA
09/2012
1Eukaryotic Initiation Factor-4EIBA
09/2012
1Mutant Proteins (Protein, Mutant)IBA
06/2011
1TensinsIBA
04/2010
1MicroRNAs (MicroRNA)IBA
04/2010
1Ribonuclease III (RNase III)IBA
04/2010
1PTEN Phosphohydrolase (PTEN Phosphatase)IBA
04/2010
1Phosphatidylinositols (Phosphatidylinositol)IBA
04/2010

Therapy/Procedure

10Therapeutics
01/2022 - 09/2012
1Immunotherapy
06/2021
1Transplantation
12/2020
1Critical Care (Surgical Intensive Care)
01/2020
1Hematopoietic Stem Cell Transplantation
01/2018
1Haploidentical Transplantation
09/2011